What is Regenerative Medicine?

Soft tissue damage through disease and injury has catapulted the development of specialized therapies that can regenerate these tissues and decrease the reliance on limited steroidal treatments or addictive opioid prescriptions for pain. Regenerative medicine, on the whole, is an interdisciplinary field that applies engineering and life science principles to promote this regeneration with the hope of restoring the diseased or injured tissues.
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Using Perinatal Tissue In Regenerative Therapies

The first reported clinical use of perinatal-derived tissue allografts for aiding in wound healing was at Johns Hopkins over a century ago in 1910. In recent years, both clinical and research applications of these biomaterials have increased in scope to include roles in tissue engineering and regenerative medicine. Perinatal tissues are an abundant source of extracellular matrix components and growth factors, with potential use in a broad array of regenerative therapies. These components have translated well to regenerative applications owing to their low immunogenicity, positive wound healing characteristics, and minimal tissue inflammation1-2. The two most widely adopted perinatal components for clinical use are the umbilical cord and the amniotic membrane.
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RHEO™ is a flowable cryopreserved human amniotic fluid allograft with extracellular matrix
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VENDAJE™ is a dehydrated human amniotic membrane allograft for wound repair
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VENDAJE™ AC is a dehydrated human amniotic membrane allograft with chorion for wound repair
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VENDAJE™ OPTIC is a dehydrated human amniotic membrane allograft for ocular repair
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1. Fukuchi, Y., Nakajima, H., Sugiyama, D., Hirose, I., Kitamura, T. and Tsuji, K. (2004), Human Placenta‐Derived Cells Have Mesenchymal Stem/Progenitor Cell Potential. STEM CELLS, 22: 649-658. doi:10.1634/stemcells.22-5-649
2. W.Page Faulk, PeterJ Stevens, Hugo Burgos, Richard Matthews, JohnP Bennett, Bae-Li Hsi, HUMAN AMNION AS AN ADJUNCT IN WOUND HEALING, The Lancet, Volume 315, Issue 8179,1980, Pages 1156-1158, ISSN 0140-6736, https://doi.org/10.1016/S0140-6736(80)91617-7