Mesenchymal Stromal Cell (MSCs): Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) are a class of stem cells with high differentiative potential, an immuno-privileged status and easy access for collection, which raise no legal or ethical issues. WJ-MSCs have immunomodulatory properties, involving both innate and adaptive immune responses.1
Bioactive ECM and Growth Factors: Adhesion G protein, Platelet Derived Growth Factor (PDGF), Epidermal Growth Factor (EGF) and Basic Fibroblast Growth Factor (bFGF).
Interleukins: IL-1RA (A natural inhibitor of the pro-inflammatory effect of IL1b), IL-2R (Promotes the differentiation of certain immature T cells into regulatory T cells), IL-4 (Inhibits classical activation of macrophages into M1 cells), and IL-13 (Mediator of allergic inflammation).
