OROPRO™

Flowable Cryopreserved Umbilical Cord and Wharton's Jelly Allograft

OROPRO™ is a cryopreserved human tissue allograft derived from the umbilical cord and the Wharton's jelly. OROPRO™ is aseptically processed to preserve the cytokines, growth factors and proteins present in Wharton's jelly for homologous use. Our CryoGen™ controlled-rate freezing process cryopreserves the allografts without significantly affecting viability.
OROPRO™ is intended for the repair, reconstruction, replacement, or supplementation of a recipient’s cells or tissues and to perform the same basic function or functions in the recipient as in the donor. The amount and administration (injected or applied topically) of the allograft is determined by the clinician based on the intended use in each patient case.

Components Present in Umbilical Cord Tissue and Wharton's Jelly

Mesenchymal Stromal Cell (MSCs): Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) are a class of stem cells with high differentiative potential, an immuno-privileged status and easy access for collection, which raise no legal or ethical issues. WJ-MSCs have immunomodulatory properties, involving both innate and adaptive immune responses.1
Bioactive ECM and Growth Factors: Adhesion G protein, Platelet Derived Growth Factor (PDGF), Epidermal Growth Factor (EGF) and Basic Fibroblast Growth Factor (bFGF).
Interleukins: IL-1RA (A natural inhibitor of the pro-inflammatory effect of IL1b), IL-2R (Promotes the differentiation of certain immature T cells into regulatory T cells), IL-4 (Inhibits classical activation of macrophages into M1 cells), and IL-13 (Mediator of allergic inflammation).

OROPRO™ is available in 1.0 and 2.0 mL sizes.

Learn More About Our Products

For more information about any of our products, please choose the appropriate option below and someone will contact you within 1 business day.

I am a Patient looking for more information

Click To Contact

I am a Health Care Provider looking for more information

Click To Contact
Thank you! We have received your information and someone will contact you shortly.
Oops! Something went wrong while submitting the form.

Contact Information

info@biostemtech.com
(954) 380-8342

2836 Center Port Circle
Pompano Beach, FL 33064

Search

Social

Links

© 2020 BioStem Technologies. All Rights Reserved. Use of this site is subject to certain Terms Of Use and Privacy Policy.
For screen reader problems with this website, please call (954) 380-8342 for assistance.

References
1. Marino L, Castaldi MA, Rosamilio R, et al. Mesenchymal Stem Cells from the Wharton's Jelly of the Human Umbilical Cord: Biological Properties and Therapeutic Potential. Int J Stem Cells. 2019;12(2):218-226. doi:10.15283/ijsc18034